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Mouse Anti-Canine Glycosylphosphatidylinositol (GPI) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for canine glycosylphosphatidylinositol. It can be applied to WB, ICC/IF, IHC and FACS assays of canine glycosylphosphatidylinositol.
Specifications
Target Information
Canine glycosylphosphatidylinositol (GPI) is a glycolipid that anchors proteins to the outer leaflet of the plasma membrane, playing a significant role in various biological processes. GPI-anchored proteins in dogs are crucial for host-parasite interactions, such as adhesion and invasion of host cells, and are considered potential diagnostic markers and drug targets for diseases like babesiosis. These proteins tend to accumulate in lipid rafts, which are critical for their functions and trafficking. The absence of GPI in higher eukaryotic cells makes it a potential pathogen-associated molecular pattern (PAMP), highlighting its importance in the immune response and as a target for vaccines and therapeutics in canine health.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.