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Mouse Anti-Porcine Protein Kinase C and Casein Kinase Substrate In Neurons 1 (PACSIN1) Monoclonal Antibody

Cat. No.VD10N119

Product TypeAnimal-targeted Antibodies

Size 100ug

Product Overview

BioVenic mouse monoclonal antibody is specific for protein kinase C and casein kinase substrate in neurons 1. It is affinity purified by protein G. It can be applied to Indirect ELISA, IF/ICC, IHC and WB assays of protein kinase C and casein kinase substrate in neurons 1.

Specifications

Application Indirect ELISA; IF/ICC; IHC; WB
Clonality Monoclonal
Classification Primary Antibody
Clone O12N20
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Protein Kinase C and Casein Kinase Substrate In Neurons 1
Isotype IgG1
Immunogen Recombinant protein of protein kinase C and casein kinase substrate in neurons 1
Purification Protein G Purified
Concentration 1mg/ml
Conjugation Unconjugated
Buffer Phosphate Buffered Saline
Physical State Liquid

Target Information

Porcine protein kinase C and casein kinase substrate in neurons 1 (PACSIN1), also known as syndapin, is a protein that plays a crucial role in the regulation of cell cytoskeleton, intracellular trafficking, and signaling. This protein is particularly important in the nervous system, where it influences neuromorphogenesis, receptor trafficking, and synaptic plasticity. PACSIN1 is known to interact with various proteins, including huntingtin and Tau, and its dysfunction has been implicated in neurodegenerative diseases such as Huntington's disease. In pigs, PACSIN1 is likely to serve similar biological functions as it does in humans and other model organisms. It is involved in the development and maintenance of the nervous system, and its activity is essential for proper neuronal function. The protein's role in synaptic vesicle recycling and endocytosis suggests that it may also play a part in the regulation of neurotransmission and neuronal communication.

Target Protein Kinase C and Casein Kinase Substrate In Neurons 1
Target Synonym Syndapin-1
Gene ID 100157037
UniProt ID A0A287AHG5

Shipping and Storage

This product is shipped with ice gel packs. Store at -80°C on receipt.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Schael, Sylvia, et al. "Casein kinase 2 phosphorylation of protein kinase C and casein kinase 2 substrate in neurons (PACSIN) 1 protein regulates neuronal spine formation." Journal of Biological Chemistry 288.13 (2013): 9303-9312.
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