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Mouse Anti-Bovine F-Box-Like/Wd Repeat-Containing Protein (FBXW) Monoclonal Antibody

Cat. No.VD12N489

Product TypeAnimal-targeted Antibodies

Size 100 μL

Product Overview

BioVenic mouse monoclonal antibody is specific for bovine F-box-like/WD repeat-containing protein. It is purified by affinity chromatography. It can be applied to WB, IHC and IF assays of bovine F-box-like/WD repeat-containing protein.

Specifications

Application WB; IHC; IF
Clonality Monoclonal
Classification Primary Antibody
Clone M5N105
Host Mouse
Target Species Bovine
Species Reactivity Bovine
Specificity Bovine F-Box-Like/WD Repeat-Containing Protein
Immunogen Recombinant protein of F-box-like/WD repeat-containing protein
Purification Purified by Affinity Chromatography
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer 0.1M Tris-Glycine, pH 7.4, with 150 mM NaCl and 50% glycerol
Physical State Liquid

Target Information

Bovine F-Box-Like/Wd Repeat-Containing Protein (FBXW7) is a key component of the SCF (SKP1-Cullin-F-box) E3 ubiquitin ligase complex, responsible for substrate recognition and ubiquitination. It targets oncoproteins such as Cyclin E, c-Myc, and Notch1 for degradation, playing a crucial role in cell cycle regulation, signal transduction, and tumor suppression. FBXW7 is highly conserved and widely expressed in various tissues, with mutations linked to cancer development.

Target Bovine F-Box-Like/WD Repeat-Containing Protein
Target Synonym TBLR1
Gene ID 540932
UniProt ID F1MNN4

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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