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Mouse Anti-Bovine CD63 Polyclonal Antibody

Cat. No.VD11N381

Product TypeAnimal-targeted Antibodies

Size 100 μg

Product Overview

BioVenic mouse polyclonal antibody is specific for bovine CD63. It is affinity purified by protein A. It can be applied to FCM assay of bovine CD63.

Specifications

Application FCM
Clonality Polyclonal
Classification Primary Antibody
Clone D25N13
Host Mouse
Target Species Bovine
Species Reactivity Bovine
Specificity Bovine CD63
Isotype IgG1
Immunogen Recombinant protein of CD63
Purification Protein A Purified
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer Sodium Azide
Buffer Phosphate Buffered Saline
Physical State Liquid

Target Information

Bovine CD63, also known as LAMP-3 (lysosome-associated membrane protein-3), is a 237 amino acid multipass transmembrane glycoprotein and a member of the tetraspanin TM4SF protein family. It is present in late endosomes, lysosomes, and secretory vesicles of various cell types, and is also found in the plasma membrane, typically following cell activation. CD63 serves as a widely used basophil activation marker and plays a role in cell activation, adhesion, motility, migration, and signal transduction in various cell types. It interacts with integrins and affects phagocytosis and cell migration, and is involved in the regulation of H/K-ATPase trafficking and ROMK1 channels. Additionally, CD63 serves as a T-cell costimulation molecule and its expression can be used for predicting the prognosis in earlier stages of carcinomas.

Target Bovine CD63
Gene ID 404156
UniProt ID Q9XSK2

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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