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Mouse Anti-Porcine ATP Citrate Synthase (ACLY) Monoclonal Antibody

Product Overview

BioVenic mouse monoclonal antibody is specific for porcine ATP citrate synthase. It is purified by affinity chromatography. It can be applied to WB, IF and FCM assays of porcine ATP citrate synthase.

Specifications

Application WB; IF; FCM

Clonality Monoclonal

Classification Primary Antibody

Clone M5N76

Host Mouse

Target Species Porcine

Species Reactivity Porcine

Specificity Porcine ATP Citrate Synthase

Immunogen Recombinant protein of ATP citrate synthase

Purification Purified by Affinity Chromatography

Concentration 1 mg/mL

Conjugation Unconjugated

Preservative and Stabilizer 0.02% Sodium Azide

Buffer 0.1M Tris-Glycine, pH 7.4, with 150 mM NaCl and 50% glycerol

Physical State Liquid

Target Information

Porcine ATP Citrate Synthase (ACLY) is a key enzyme responsible for synthesizing cytosolic acetyl-CoA from citrate and CoA, playing a crucial role in lipid metabolism and cholesterol synthesis. This enzyme is essential for cellular energy balance and is involved in multiple biosynthetic pathways, including fatty acid and cholesterol production. ACLY is also implicated in cancer metabolism due to its role in providing acetyl-CoA for tumor growth.

Target Porcine ATP Citrate Synthase

Target Synonym ACLY

Gene ID 397519

UniProt ID G1FJ20

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Kosicki, George W., and Leo PK Lee. "Effect of divalent metal ions on nucleotide inhibition of pig heart citrate synthase." Journal of Biological Chemistry 241.15 (1966): 3571-3574.