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Mouse Anti-Porcine Syntaxin Binding Protein 1 (STXBP1) Monoclonal Antibody

Cat. No.VD8N402

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for syntaxin binding protein 1. It is affinity purified by protein A. It can be applied to WB, IF, IHC and ELISA assays of syntaxin binding protein 1.

Specifications

Application WB; IF; IHC; ELISA
Clonality Monoclonal
Classification Primary Antibody
Clone G9N2
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Syntaxin Binding Protein 1
Isotype IgG2
Immunogen Recombinant protein of syntaxin binding protein 1
Purification Protein A Purified
Concentration 2500 μg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline with 50% Glycerol, pH 7.3
Physical State Liquid

Target Information

Porcine syntaxin binding protein 1 (pSTXBP1), also known as Munc18-1, is a crucial regulatory protein involved in the modulation of neurotransmitter release at the synapses of neuronal cells. pSTXBP1 interacts with syntaxin, a major component of the SNARE complex, which is essential for the fusion of vesicles with the plasma membrane and the subsequent release of neurotransmitters. This protein plays a vital role in the control of synaptic vesicle exocytosis, ensuring the proper timing and amount of neurotransmitter released in response to neuronal activity. In pigs, pSTXBP1 is expressed in the brain and contributes to the regulation of neurotransmission, which is critical for normal cognitive function and behavior.

Target Syntaxin Binding Protein 1
Target Synonym EIEE4; FLJ37475
Gene ID 100517927
UniProt ID F1RS11

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Grone, Brian P., et al. "Epilepsy, behavioral abnormalities, and physiological comorbidities in syntaxin-binding protein 1 (STXBP1) mutant zebrafish." Plos one 11.3 (2016): e0151148.
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