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Rabbit Anti-Chicken Interleukin 10 (IL10) Polyclonal Antibody

Cat. No.VD12N151

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for chicken interleukin 10. It is affinity purified by protein A. It can be applied to WB, IHC and IF/ICC assays of chicken interleukin 10.

Specifications

Application WB; IHC; IF/ICC
Clonality Polyclonal
Classification Primary Antibody
Clone F12N21
Host Rabbit
Target Species Chicken
Species Reactivity Chicken
Specificity Chicken Interleukin 10
Immunogen Recombinant protein of interleukin 10
Purification Protein A Purified
Concentration 0.98 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, 50% Glycerol
Physical State Liquid

Target Information

Chicken interleukin 10 (IL-10) is an anti-inflammatory cytokine produced by various immune cells, including T helper cells, macrophages, and B cells. It plays a crucial role in immune regulation by downregulating the expression of pro-inflammatory cytokines such as IL-1β, TNF-α, and IFN-γ. IL-10 also inhibits the production of reactive oxygen species and nitric oxide, thereby reducing tissue damage during inflammation. Additionally, it enhances B cell survival, proliferation, and antibody production. IL-10 signals through a receptor complex consisting of IL-10R1 and IL-10R2, leading to the activation of the JAK-STAT signaling pathway.

Target Chicken Interleukin 10
Target Synonym IL10
Gene ID 428264
UniProt ID Q6A2H4

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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