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Mouse Anti-Canine KDEL Receptor Monoclonal Antibody

Cat. No.VD11N235

Product TypeAnimal-targeted Antibodies

Size 50 μL

Product Overview

BioVenic mouse monoclonal antibody is specific for canine KDEL Receptor. It can be applied to WB, ICC/IF and IP assays of canine KDEL Receptor.

Specifications

Application WB; ICC/IF; IP
Clonality Monoclonal
Classification Primary Antibody
Clone S18N37
Host Mouse
Target Species Canine
Species Reactivity Canine
Specificity Canine KDEL Receptor
Isotype IgG1
Immunogen Recombinant protein of KDEL receptor
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.09% Sodium Azide
Buffer Phosphate Buffered Saline
Physical State Liquid

Target Information

Canine KDEL receptor is a crucial protein involved in the retrieval of ER-resident proteins from the Golgi to the endoplasmic reticulum (ER), a process essential for maintaining ER protein homeostasis. It recognizes and binds to proteins with a C-terminal KDEL sequence, initiating their return to the ER via COPI vesicles. This receptor plays a significant role in the unfolded protein response (UPR), which is a cellular stress response to ER stress, and is implicated in diseases associated with ER stress and protein misfolding. The KDEL receptor's function in protein trafficking and its involvement in the UPR make it a potential target for therapeutic interventions in canine diseases related to protein homeostasis and neurodegenerative conditions.

Target Canine KDEL Receptor
Target Synonym KDEL endoplasmic reticulum protein retention receptor
Gene ID 484406
UniProt ID A0A8I3MFZ0

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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