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Mouse Anti-Canine KDEL Receptor Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for canine KDEL Receptor. It can be applied to WB, ICC/IF and IP assays of canine KDEL Receptor.
Specifications
Target Information
Canine KDEL receptor is a crucial protein involved in the retrieval of ER-resident proteins from the Golgi to the endoplasmic reticulum (ER), a process essential for maintaining ER protein homeostasis. It recognizes and binds to proteins with a C-terminal KDEL sequence, initiating their return to the ER via COPI vesicles. This receptor plays a significant role in the unfolded protein response (UPR), which is a cellular stress response to ER stress, and is implicated in diseases associated with ER stress and protein misfolding. The KDEL receptor's function in protein trafficking and its involvement in the UPR make it a potential target for therapeutic interventions in canine diseases related to protein homeostasis and neurodegenerative conditions.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.