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Mouse Anti-Bovine Lysine-Specific Demethylase 1A (LSD1) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for bovine lysine-specific demethylase 1A. It can be applied to WB, IHC, IF and ICC assays of bovine lysine-specific demethylase 1A.
Specifications
Target Information
LSD1, or lysine-specific demethylase 1A, is an enzyme with a unique function in the regulation of gene expression through its demethylase activity. It is primarily known for its ability to remove methyl groups from mono- and dimethylated lysine 4 on histone H3 (H3K4me1/2), a modification associated with active gene transcription. LSD1's action counterbalances the methylation marks added by histone methyltransferases, thus playing a critical role in the dynamic regulation of chromatin structure. Its demethylase activity is not limited to histones; LSD1 can also demethylate non-histone proteins, including the tumor suppressor p53, further emphasizing its broad impact on cellular processes.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt. Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Magliulo, Daniela, et al. "Lysine-specific demethylase 1A as a promising target in acute myeloid leukemia." Frontiers in Oncology 8 (2018): 255.