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Mouse Anti-Porcine Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 3 (CHCHD3) Monoclonal Antibody

Cat. No.VD8N348

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for coiled-coil-helix-coiled-coil-helix domain containing 3. It is affinity purified by protein A. It can be applied to WB, IF and ELISA assays of coiled-coil-helix-coiled-coil-helix domain containing 3.

Specifications

Application WB; IF; ELISA
Clonality Monoclonal
Classification Primary Antibody
Clone G8N1
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 3
Isotype IgG2
Immunogen Recombinant protein of coiled-coil-helix-coiled-coil-helix domain containing 3
Purification Protein A Purified
Concentration 1000 μg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline with 50% Glycerol, pH 7.3
Physical State Liquid

Target Information

Porcine coiled-coil-helix-coiled-coil-helix domain containing 3 (pCHCHD3) is a protein that belongs to the coiled-coil-helix-coiled-coil-helix (CHCH) domain family. This family is characterized by a unique structural motif that consists of coiled-coil regions flanking a central helix, which imparts specific functions in protein-protein interactions and cellular organization. pCHCHD3 plays a role in mitochondrial function, particularly in the maintenance of mitochondrial morphology and dynamics. It is involved in the regulation of mitochondrial fusion and fission, processes critical for the proper distribution of mitochondrial content within cells and the removal of damaged mitochondria through a process called mitophagy.

Target Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 3
Target Synonym CHCHD3; FLJ20420
Gene ID 414383
UniProt ID A0A286ZUS4

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Darshi, Manjula, et al. "Targeting and import mechanism of coiled-coil helix coiled-coil helix domain-containing protein 3 (ChChd3) into the mitochondrial intermembrane space." Journal of Biological Chemistry 287.47 (2012): 39480-39491.
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