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Mouse Anti-Sheep Ryanodine Receptor Monoclonal Antibody

Cat. No.VD11N165

Product TypeAnimal-targeted Antibodies

Size 100 μL

Product Overview

BioVenic mouse monoclonal antibody is specific for sheep ryanodine receptor. It can be applied to WB, ICC/IF, IHC and IP assays of sheep ryanodine receptor.

Specifications

Application WB; ICC/IF; IHC; IP
Clonality Monoclonal
Classification Primary Antibody
Clone S15N5
Host Mouse
Target Species Sheep
Species Reactivity Sheep
Specificity Sheep Ryanodine Receptor
Isotype IgG1
Immunogen Recombinant protein of ryanodine receptor
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Sodium Azide
Buffer Phosphate Buffered Saline
Physical State Liquid

Target Information

Sheep ryanodine receptor (RyR) is a key calcium release channel found in the sarcoplasmic reticulum of skeletal and cardiac muscles. It plays a pivotal role in the process of excitation-contraction coupling, which is essential for muscle contraction. The RyR channel is activated by an increase in intracellular calcium levels and facilitates the release of calcium stores within the muscle cells, leading to muscle contraction. Mutations in the RyR gene have been associated with several muscle diseases, including malignant hyperthermia, making it a significant target for understanding and potentially treating muscle-related conditions in sheep.

Target Sheep Ryanodine Receptor
Target Synonym RYR; Skeletal muscle ryanodine receptor; Type 1 ryanodine receptor
Gene ID 101112591
UniProt ID A0A836A130

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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