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Mouse Anti-Sheep Ryanodine Receptor Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for sheep ryanodine receptor. It can be applied to WB, ICC/IF, IHC and IP assays of sheep ryanodine receptor.
Specifications
Target Information
Sheep ryanodine receptor (RyR) is a key calcium release channel found in the sarcoplasmic reticulum of skeletal and cardiac muscles. It plays a pivotal role in the process of excitation-contraction coupling, which is essential for muscle contraction. The RyR channel is activated by an increase in intracellular calcium levels and facilitates the release of calcium stores within the muscle cells, leading to muscle contraction. Mutations in the RyR gene have been associated with several muscle diseases, including malignant hyperthermia, making it a significant target for understanding and potentially treating muscle-related conditions in sheep.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.