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Rabbit Anti-Equine IgG Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for equine IgG. It is affinity purified by protein A. It can be applied to WB, IHC and IF/ICC assays of equine IgG.
Specifications
Target Information
Equine IgG is the principal immunoglobulin found in the plasma of horses, representing up to 80% of the total immunoglobulin concentration. It plays a critical role in the equine immune system, with various subclasses identified, including IgGa, IgGb, IgGc, and IgG(T), which have been reassigned as IgG1 to IgG7 with the advancement in genetic understanding. These subclasses have different effector functions, with IgG1, IgG3, IgG4, IgG5, and IgG7 being able to elicit a strong respiratory burst from equine peripheral blood leukocytes and activate complement via the classical pathway, suggesting their importance in immune responses.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Lewis, Melanie J., et al. "The different effector function capabilities of the seven equine IgG subclasses have implications for vaccine strategies." Molecular immunology 45.3 (2008): 818-827.