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Mouse Anti-Porcine L-Dopachrome Tautomerase (DCT) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for l-dopachrome tautomerase. It is affinity purified by protein G. It can be applied to WB, IF and ELISA assays of l-dopachrome tautomerase.
Specifications
Target Information
Porcine L-dopachrome tautomerase, also known as DOPT or APOH, is an enzyme that plays a pivotal role in the melanin biosynthesis pathway. This protein catalyzes the isomerization of L-dopachrome to 5,6-dihydroxyindole, which is a key step in the production of melanin pigments. Beyond its function in pigment production, DOPT has also been implicated in various physiological and pathological processes, including the immune response and the progression of neurodegenerative diseases. As a molecular target, DOPT is significant due to its dual role in melanogenesis and its potential involvement in disease pathology. It has been studied in the context of pigmentation disorders and melanoma, as well as in conditions such as Alzheimer's disease, where its expression levels have been found to be altered.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Popa, Ioana L., et al. "Cross-talk between dopachrome tautomerase and caveolin-1 is melanoma cell phenotype-specific and potentially involved in tumor progression." Journal of Biological Chemistry 291.24 (2016): 12481-12500.