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Mouse Anti-Porcine Protein Phosphatase 2A Catalytic (PP2A-C) Alpha Monoclonal Antibody

Cat. No.VD8N125

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for porcine protein phosphatase 2A catalytic alpha. It can be applied to WB, IF and ICC assays of porcine protein phosphatase 2A catalytic alpha.

Specifications

Application WB; IF; ICC
Clonality Monoclonal
Classification Primary Antibody
Clone G3N89
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Porcine Protein Phosphatase 2A Catalytic Alpha
Isotype IgG
Immunogen Purified recombinant porcine protein phosphatase 2A catalytic alpha (N-terminus) protein fragments
Concentration 1 mg/mL
Conjugation Unconjugated
Physical State Liquid

Target Information

Protein phosphatase 2A catalytic alpha (PP2A-Cα) is a subunit of the PP2A complex, which is a highly conserved serine/threonine phosphatase involved in a multitude of cellular processes. PP2A is composed of a scaffold A subunit, a catalytic C subunit, and a regulatory B subunit, with the Cα subunit being one of the isoforms of the catalytic subunit. PP2A-Cα plays a critical role in reversing the effects of protein kinases by removing phosphate groups from serine and threonine residues on target proteins. This activity is essential for the regulation of cell growth, division, and the maintenance of cellular homeostasis. The PP2A complex is also implicated in the control of signal transduction pathways, including those involved in apoptosis and the response to DNA damage.

Target Porcine Protein Phosphatase 2A Catalytic Alpha
Target Synonym PPP2CA
Gene ID 397656
UniProt ID P67776

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt. Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Gergs, Ulrich, et al. "Overexpression of the catalytic subunit of protein phosphatase 2A impairs cardiac function." Journal of Biological Chemistry 279.39 (2004): 40827-40834.
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