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Rabbit Anti-Chicken DNA Methyltransferase 3B (Dnmt3b) Polyclonal Antibody

Cat. No.VD8N1

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for chicken DNA methyltransferase 3B. It can be applied to WB, IHC, IF and ELISA assays of chicken DNA methyltransferase 3B.

Specifications

Application WB; IHC; IF; ELISA
Clonality Polyclonal
Classification Primary Antibody
Clone G2N1
Host Rabbit
Target Species Chicken
Species Reactivity Chicken
Specificity Chicken DNA Methyltransferase 3B
Isotype IgG
Immunogen Synthesized peptide derived from chicken DNA methyltransferase 3B
Concentration 1 mg/mL
Conjugation Unconjugated
Physical State Liquid

Target Information

Chicken DNA methyltransferase 3B (cDNMT3B) is a key enzyme responsible for establishing de novo DNA methylation patterns during early chicken development. As a member of the DNA methyltransferase family, cDNMT3B is instrumental in adding a methyl group to the cytosine base of DNA, which can alter gene expression without changing the DNA sequence. This process is vital for various biological functions, including genomic imprinting, X-chromosome inactivation, and the suppression of transposable elements.

Target Chicken DNA Methyltransferase 3B
Target Synonym DNMT3B; DNA (Cytosine-5)-Methyltransferase 3B
Gene ID 419287
UniProt ID Q4W5Z3

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt. Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Lin, Chien-Chu, et al. "Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B." Nucleic acids research 48.7 (2020): 3949-3961.
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