Mouse Anti-Porcine Heme Oxygenase 1 (HMOX1) Monoclonal Antibody

Porcine heme oxygenase 1 (HO-1), also known as heat shock protein 32 (HSP32), is a stress-responsive enzyme found in pigs. It is a key member of the heat shock protein family and plays a significant role in the cellular response to oxidative stress, inflammation, and other forms of cellular injury. HO-1 catalyzes the degradation of heme, a component of hemoglobin, into biliverdin, iron, and carbon monoxide, which are all involved in various physiological and pathophysiological processes. The enzyme's expression is upregulated in response to various stimuli, including heat shock, ultraviolet radiation, and cytokines, serving as a cytoprotective mechanism. HO-1's induction is associated with anti-inflammatory, antioxidant, and anti-apoptotic properties, making it a critical target for research into diseases characterized by oxidative stress and inflammation, such as sepsis and ischemia-reperfusion injuries.