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Mouse Anti-Swine CD18 Monoclonal Antibody
Product Overview
O10H13 monoclonal antibody is specific for Swine CD18, also know as Swine ITGB2 or LFA-1. It was purified by affinity chromatography on Protein G from tissue culture supernatant. It can be applied for Flow Cytometry (FC); Functional Assays (FN) and Immunoprecipitation (IP).
Specifications
Target Information
Cluster of differentiation 18 (CD18) is the most recently defined member of the leukocyte integrin family and is expressed on tissue macrophages, dendritic cells, and eosinophils and binds to ICAM-3 and vascular cell adhesion molecule-l (VCAM-l). CD18 plays a critical role in cell such as, cell adhesion, trafficking and T cell effector function. CD 18 gene expression by porcine alveolar macrophages appears not to be regulated by human proinflammatory cytokines.
Shipping and Storage
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt (up to 12 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
References
- Bergh, Philippe GAC Vanden, et al. "The wild boar (Sus scrofa) Lymphocyte function-associated antigen-1 (CD11a/CD18) receptor: cDNA sequencing, structure analysis and comparison with homologues." BMC Veterinary Research 3 (2007): 1-12.