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Rabbit Anti-Canine Annexin A4 (ANXA4) Polyclonal Antibody

Cat. No.VD11N608

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for canine annexin A4. It is affinity purified by protein G. It can be applied to ELISA assay of canine annexin A4.

Specifications

Application ELISA
Clonality Polyclonal
Classification Primary Antibody
Clone J3N21
Host Rabbit
Target Species Canine
Species Reactivity Canine
Specificity Canine Annexin A4
Isotype IgG
Immunogen Recombinant protein of annexin A4
Purification Protein G Purified
Purity > 95%
Conjugation Unconjugated
Preservative and Stabilizer 0.03% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, 50% Glycerol
Physical State Liquid

Target Information

Bovine annexin A4 is a calcium-dependent, membrane-binding protein that has been shown to play a role in restoring cytokinesis in bacteria, particularly when this process is inhibited by beta-lactam antibiotics such as ampicillin, piperacillin, and cephalexin. This novel activity of Annexin A4 is crucial as it can reverse the inhibitory effects on cytokinesis, which is the final step in cell division. The mechanism of action of Annexin A4 depends on calcium binding, and its binding to membranes is essential for restoring cytokinesis. The filamentous form of bacteria, which is more resistant to phagocytosis by immune cells, can be reduced by the expression of Annexin A4, potentially enhancing the efficacy of antibiotic chemotherapy.

Target Canine Annexin A4
Target Synonym ANXA4; Annexin IV; Chromobindin-4
Gene ID 281625
UniProt ID P13214

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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