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Mouse Anti-Chicken Melanoma Cell Adhesion Molecule (MCAM) Monoclonal Antibody-[PE]

Product Overview

BioVenic mouse monoclonal antibody is specific for chicken melanoma cell adhesion molecule. It can be applied to FCM and IP assays of chicken melanoma cell adhesion molecule.

Specifications

Application FCM; IP

Clonality Monoclonal

Classification Primary Antibody

Clone L11N23

Host Mouse

Target Species Chicken

Species Reactivity Chicken; Avian

Specificity Chicken Melanoma Cell Adhesion Molecule

Isotype IgG2

Immunogen Mixture of E15 and E16 thymocytes from chicken embryos

Purity > 90%

Concentration 0.1 mg/mL

Conjugation PE

Preservative and Stabilizer < 0.1% Sodium Azide

Buffer Phosphate Buffered Saline with Stabilizer

Physical State Liquid

Target Information

Chicken melanoma cell adhesion molecule, also known as CD146, is a cell surface glycoprotein that is a member of the immunoglobulin superfamily. It is involved in cell-cell adhesion and is expressed in various tissues, including melanoma cells, endothelial cells, and some immune cells. cMCAM plays a role in cellular adhesion, migration, and tissue organization. It is implicated in the maintenance of tissue integrity and has been associated with the regulation of angiogenesis, which is essential for tumor growth and metastasis in melanoma.

Target Chicken Melanoma Cell Adhesion Molecule

Target Synonym CD146; MCAM

Gene ID 448832; 100549798

Shipping and Storage

This product is shipped with ice gel packs. Store at 2°C - 8°C (up to 12 months) on receipt. Avoid exposure to light and do not freeze.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Wang, Zhaoqing, et al. "CD146, from a melanoma cell adhesion molecule to a signaling receptor." Signal transduction and targeted therapy 5.1 (2020): 148.