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Mouse Anti-Chicken TCRγδ Monoclonal Antibody-[PE]

Cat. No.VD7N238

Product TypeAnimal-targeted Antibodies

Size 0.1 mg

Product Overview

BioVenic mouse monoclonal antibody is specific for chicken TCRγδ. It can be applied to FCM, IHC and IP assays of chicken TCRγδ.

Specifications

Application FCM; IHC; IP
Clonality Monoclonal
Classification Primary Antibody
Clone L10N52
Host Mouse
Target Species Chicken
Species Reactivity Chicken
Specificity Chicken TCRγδ
Isotype IgG1
Immunogen Outbred chicken thymocytes and Ig-negative blood lymphocytes
Purity > 90%
Concentration 0.1 mg/mL
Conjugation PE
Preservative and Stabilizer < 0.1% Sodium Azide
Buffer Phosphate Buffered Saline with Stabilizer
Physical State Liquid

Target Information

Chicken T cell receptor gamma delta (cTCRγδ) is a unique isoform of the T cell receptor (TCR) found on the surface of γδ T cells in chickens. These cells are a subset of T lymphocytes that possess a distinct TCR composed of γ (gamma) and δ (delta) chains, as opposed to the more common α (alpha) and β (beta) chains found on αβ T cells. The cTCRγδ is involved in the recognition of non-peptide antigens, such as phospholipids and small metabolites, which are presented by non-classical MHC molecules. This allows γδ T cells to respond rapidly to certain pathogens and to participate in innate-like immune responses. They also contribute to tissue homeostasis and have been implicated in mucosal immunity

Target Chicken TCRγδ
Target Synonym T3/TCR complex; TCR gamma/delta

Shipping and Storage

This product is shipped with ice gel packs. Store at 2°C - 8°C (up to 12 months) on receipt. Avoid exposure to light and do not freeze.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Hearn, Cari J., et al. "Contribution of the TCRβ Repertoire to Marek's Disease Genetic Resistance in the Chicken." Viruses 15.3 (2023): 607.
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