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Rabbit Anti-Porcine Interferon Gamma (IFNg) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for porcine interferon gamma. It is affinity purified by protein A. It can be applied to WB, IHC and IF/ICC assays of porcine interferon gamma.
Specifications
Target Information
Porcine interferon gamma (IFN-γ) is a cytokine produced by activated T cells and natural killer (NK) cells in pigs, with broad-spectrum antiviral activity and immunomodulatory functions. It plays a crucial role in immune regulation by activating the body's innate immunity against viral attacks. IFN-γ does not directly kill viruses but instead binds to cell surface receptors, inducing the production of antiviral proteins such as ADAR, PKR, Mx, OAS, and RNaseL, which inhibit viral replication and translation. This cytokine is also involved in the regulation of other cytokines and acts synergistically with them, activating through the binding of IFN-γ receptor I and II, and the JAK-STAT pathway.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Manirarora, Jean N., et al. "Development and characterization of new monoclonal antibodies against porcine interleukin-17A and interferon-gamma." Frontiers in Immunology 13 (2022): 786396.