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Mouse Anti-Porcine Secreted Frizzled-Related Protein 2 (SFRP2) Monoclonal Antibody

Cat. No.VD8N406

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for secreted frizzled-related protein 2. It is affinity purified by protein A. It can be applied to WB, IF, IHC and ELISA assays of secreted frizzled-related protein 2.

Specifications

Application WB; IF; IHC; ELISA
Clonality Monoclonal
Classification Primary Antibody
Clone G9N6
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Secreted Frizzled-Related Protein 2
Isotype IgG1
Immunogen Recombinant protein of secreted frizzled-related protein 2
Purification Protein A Purified
Concentration 1000 μg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline with 50% Glycerol, pH 7.3
Physical State Liquid

Target Information

Porcine secreted frizzled-Related Protein 2 (pSFRP2) is a secreted protein that belongs to the family of Frizzled-related proteins, which are known to play roles in the modulation of Wnt signaling pathways. These pathways are integral to various developmental processes, cellular differentiation, and tissue homeostasis in pigs. pSFRP2, in particular, acts as a regulator of Wnt signaling by competing with Wnt ligands for binding to Frizzled receptors and LRP (Low-Density Lipoprotein Receptor-Related Protein) co-receptors. This interaction inhibits the activation of the Wnt pathway, which is crucial for controlling cell proliferation, migration, and the self-renewal of stem cells.

Target Secreted Frizzled-Related Protein 2
Target Synonym FRP 2; FRP2
Gene ID 100516027
UniProt ID F1RX31

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. van Loon, Karlijn, et al. "Secreted frizzled-related protein 2: a key player in noncanonical Wnt signaling and tumor angiogenesis." Cancer and Metastasis Reviews 40 (2021): 191-203.
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