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Mouse Anti-Porcine Phosphodiesterase 4D (PDE4D) Monoclonal Antibody

Cat. No.VD8N386

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for phosphodiesterase 4D. It is affinity purified by protein G. It can be applied to WB, IF and ELISA assays of phosphodiesterase 4D.

Specifications

Application WB; IF; ELISA
Clonality Monoclonal
Classification Primary Antibody
Clone G8N39
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Phosphodiesterase 4D
Isotype IgG1
Immunogen Recombinant protein of phosphodiesterase 4D
Purification Protein G Purified
Concentration 1600 μg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline with 50% Glycerol, pH 7.3
Physical State Liquid

Target Information

Porcine phosphodiesterase 4D (pPDE4D) is a key enzyme within the phosphodiesterase family, which is responsible for the hydrolysis of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP), two important secondary messengers in cellular signaling. pPDE4D plays a crucial role in regulating the levels of these cyclic nucleotides, thereby modulating various physiological processes such as inflammation, immune responses, and the relaxation of smooth muscle cells. This enzyme is highly expressed in tissues such as the heart, brain, and lungs, where it contributes to the fine-tuning of cellular responses to hormonal and neuronal stimuli. In pigs, pPDE4D may be particularly important for the regulation of cardiovascular function and the modulation of inflammatory responses, which are critical for maintaining health and homeostasis.

Target Phosphodiesterase 4D
Target Synonym DPDE3; HSPDE4D
Gene ID 100512964
UniProt ID A0A4X1UWR8

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Taskén, Kristin A., et al. "Phosphodiesterase 4D and protein kinase a type II constitute a signaling unit in the centrosomal area." Journal of Biological Chemistry 276.25 (2001): 21999-22002.
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