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Mouse Anti-Porcine Phosphodiesterase 4D (PDE4D) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for phosphodiesterase 4D. It is affinity purified by protein G. It can be applied to WB, IF and ELISA assays of phosphodiesterase 4D.
Specifications
Target Information
Porcine phosphodiesterase 4D (pPDE4D) is a key enzyme within the phosphodiesterase family, which is responsible for the hydrolysis of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP), two important secondary messengers in cellular signaling. pPDE4D plays a crucial role in regulating the levels of these cyclic nucleotides, thereby modulating various physiological processes such as inflammation, immune responses, and the relaxation of smooth muscle cells. This enzyme is highly expressed in tissues such as the heart, brain, and lungs, where it contributes to the fine-tuning of cellular responses to hormonal and neuronal stimuli. In pigs, pPDE4D may be particularly important for the regulation of cardiovascular function and the modulation of inflammatory responses, which are critical for maintaining health and homeostasis.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Taskén, Kristin A., et al. "Phosphodiesterase 4D and protein kinase a type II constitute a signaling unit in the centrosomal area." Journal of Biological Chemistry 276.25 (2001): 21999-22002.