This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Mouse Anti-Canine Forkhead Box A1 (FOXA1) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for canine forkhead box A1. It can be applied to WB and ICC/IF assays of canine forkhead box A1.
Specifications
Target Information
Canine forkhead box A1 (FOXA1) is a transcription factor that plays a pivotal role in development and cancer progression. FOXA1 is required for the normal development of mammary glands and prostate, and it is crucial for estrogen receptor (ER) and androgen receptor (AR)-regulated transcription in hormone receptor-positive breast and prostate cancers. FOXA1 binding to nucleosomes induces an open chromatin configuration, enabling the recruitment of other transcriptional regulators, and is often referred to as a 'pioneering' factor. Understanding FOXA1's function in development provides insight into its role in cancer, making it a significant target for therapeutic interventions in canine health, particularly in managing hormone-related cancers.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.