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Rabbit Anti-Bovine Angiopoietin 1 (ANG1) Polyclonal Antibody-[Detection]
Product Overview
BioVenic rabbit polyclonal antibody is specific for bovine angiopoietin 1. It is affinity purified by protein G. It can be applied to ELISA assay of bovine angiopoietin 1. The clone J2N5 can be used as capture antibody in the ELISA assay, and the clone J2N6 can be used as detection antibody in the ELISA assay.
Specifications
Target Information
Bovine angiopoietin 1 (Ang-1) is a critical growth factor that acts on the Tie receptor family, predominantly expressed in endothelial cells and crucial for vascular development and homeostasis. It plays a significant role in angiogenesis, the maturation of newly-formed vessels, and the maintenance of vascular integrity. Ang-1 is known for its vascular protective effects, such as suppressing plasma leakage, inhibiting vascular inflammation, and preventing endothelial cell death. It also has the potential to regulate microvascular reactivity and protect the microcirculation during acute endothelial dysfunction through the eNOS and VE-cadherin signaling pathways.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Nguyen, Vicky PKH, et al. "Differential response of lymphatic, venous and arterial endothelial cells to angiopoietin-1 and angiopoietin-2." BMC cell biology 8 (2007): 1-16.