Mouse Anti-Porcine Alanine Aminotransferase 1 (ALT1) Monoclonal Antibody

Porcine alanine aminotransferase 1 (ALT1) is a crucial enzyme involved in the metabolic pathways of amino acids, specifically catalyzing the transfer of an amino group from alanine to α-ketoglutarate to form pyruvate and glutamate. This enzyme is widely distributed in various tissues of the pig, with particularly high expression levels in the liver, making it a sensitive indicator of liver damage when its levels are elevated in serum. However, it is also expressed in other tissues such as the kidneys, skeletal muscle, and gastrointestinal tract, which can complicate the interpretation of serum ALT levels as a liver-specific marker. In pigs, ALT1 plays a vital role in gluconeogenesis and provides energy for muscle contraction and other physiological processes. Its high sensitivity to liver cell damage makes it a valuable diagnostic tool in veterinary medicine for monitoring liver health and detecting liver diseases such as hepatitis and cirrhosis. The enzyme's activity can also be influenced by factors like diet, exercise, and certain medications, which should be considered when interpreting serum ALT levels.