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Mouse Anti-Canine TFIIH Basal Transcription Factor Complex Helicase XPB Subunit (TFIIH) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for canine TFIIH basal transcription factor complex helicase XPB subunit. It is purified by affinity chromatography. It can be applied to WB assay of canine TFIIH basal transcription factor complex helicase XPB subunit.
Specifications
Target Information
Canine TFIIH Basal Transcription Factor Complex Helicase XPB (XPB) is a core subunit of the TFIIH complex, essential for both transcription initiation and DNA repair. It functions as an ATP-dependent DNA helicase, unwinding DNA during nucleotide excision repair (NER) and transcription initiation by RNA polymerase II. XPB is involved in resolving DNA damage and maintaining genomic stability. Mutations in XPB are associated with severe genetic disorders such as xeroderma pigmentosum (XP) and trichothiodystrophy (TTD), highlighting its critical role in DNA repair.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.