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Mouse Anti-Canine TFIIH Basal Transcription Factor Complex Helicase XPB Subunit (TFIIH) Monoclonal Antibody

Cat. No.VD12N436

Product TypeAnimal-targeted Antibodies

Size 100 μL

Product Overview

BioVenic mouse monoclonal antibody is specific for canine TFIIH basal transcription factor complex helicase XPB subunit. It is purified by affinity chromatography. It can be applied to WB assay of canine TFIIH basal transcription factor complex helicase XPB subunit.

Specifications

Application WB
Clonality Monoclonal
Classification Primary Antibody
Clone M5N50
Host Mouse
Target Species Canine
Species Reactivity Canine
Specificity Canine TFIIH Basal Transcription Factor Complex Helicase XPB Subunit
Immunogen Recombinant protein of TFIIH basal transcription factor complex helicase XPB subunit
Purification Purified by Affinity Chromatography
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer 0.1M Tris-Glycine, pH 7.4, with 150 mM NaCl and 50% glycerol
Physical State Liquid

Target Information

Canine TFIIH Basal Transcription Factor Complex Helicase XPB (XPB) is a core subunit of the TFIIH complex, essential for both transcription initiation and DNA repair. It functions as an ATP-dependent DNA helicase, unwinding DNA during nucleotide excision repair (NER) and transcription initiation by RNA polymerase II. XPB is involved in resolving DNA damage and maintaining genomic stability. Mutations in XPB are associated with severe genetic disorders such as xeroderma pigmentosum (XP) and trichothiodystrophy (TTD), highlighting its critical role in DNA repair.

Target Canine TFIIH Basal Transcription Factor Complex Helicase XPB Subunit
Target Synonym TFIIH
Gene ID 476105
UniProt ID A0A8P0PG66

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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