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Mouse Anti-Porcine Alpha 1 Antitrypsin Monoclonal Antibody

Cat. No.VD8N226

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for alpha 1 antitrypsin. It is affinity purified by protein A. It can be applied to WB, IP, IF, IHC and ELISA assays of alpha 1 antitrypsin.

Specifications

Application WB; IP; IF; IHC; ELISA
Clonality Monoclonal
Classification Primary Antibody
Clone G5N39
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Alpha 1 Antitrypsin
Isotype IgG1
Immunogen Recombinant protein of alpha 1 antitrypsin
Purification Protein A Purified
Concentration 2280 μg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline with 50% Glycerol, pH 7.3
Physical State Liquid

Target Information

Porcine alpha-1 antitrypsin (pA1AT) is a serine protease inhibitor that plays a crucial role in the innate immune system of pigs. It is primarily produced in the liver and circulates in the blood, where it serves to protect tissues from the damaging effects of proteolytic enzymes, particularly neutrophil elastase. pA1AT is known for its ability to inhibit a variety of proteases, which are enzymes that break down proteins. By doing so, it helps to maintain tissue integrity and prevent uncontrolled proteolysis that can occur during inflammation and infection. The protein is also implicated in the regulation of inflammation and immune responses.

Target Alpha 1 Antitrypsin
Target Synonym A1A; A-1-antitrypsin
UniProt ID P50447

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Torres-Durán, María, et al. "Alpha-1 antitrypsin deficiency: outstanding questions and future directions." Orphanet journal of rare diseases 13 (2018): 1-15.
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