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Mouse Anti-Porcine LIM Domain Kinase 1 (LIMK1) Monoclonal Antibody

Product Overview

BioVenic mouse monoclonal antibody is specific for LIM domain kinase 1. It is affinity purified by protein A. It can be applied to WB, IF and Indirect ELISA assays of LIM domain kinase 1.

Specifications

Application WB; IF; Indirect ELISA

Clonality Monoclonal

Classification Primary Antibody

Clone O11N99

Host Mouse

Target Species Porcine

Species Reactivity Porcine

Specificity LIM Domain Kinase 1

Isotype IgG2

Immunogen Recombinant protein of LIM domain kinase 1

Purification Protein A Purified

Concentration 1 mg/mL

Conjugation Unconjugated

Buffer Phosphate Buffered Saline

Physical State Liquid

Target Information

Porcine LIM domain kinase 1 (LIMK1) is a serine/threonine protein kinase that plays a pivotal role in the regulation of the actin cytoskeleton. This enzyme is particularly important for processes such as cell invasion, proliferation, cytokinesis, adhesion, and differentiation. LIMK1 is unique in its ability to phosphorylate the actin depolymerizing factor, cofilin, on serine-3, leading to the suppression of actin filament severing and thereby influencing cellular dynamics.

Target LIM Domain Kinase 1

Gene ID 100627618

UniProt ID A0A4X1UTR2

Shipping and Storage

This product is shipped with ice gel packs. Store at -80°C on receipt.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Davila, Monica, et al. "LIM kinase 1 is essential for the invasive growth of prostate epithelial cells: implications in prostate cancer." Journal of Biological Chemistry 278.38 (2003): 36868-36875.