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Mouse Anti-Bovine CD86 Monoclonal Antibody-[PE]
Product Overview
BioVenic mouse monoclonal antibody is specific for bovine CD86. It can be applied to FCM assay of bovine CD86.
Specifications
Target Information
Bovine CD86, also known as B7-2, is a co-stimulatory molecule expressed on antigen-presenting cells such as dendritic cells, macrophages, and B cells. It plays a crucial role in T cell activation by interacting with the T cell receptors CD28 and CTLA-4. The binding of CD86 to CD28 provides a necessary co-stimulatory signal for T cell proliferation and differentiation, while its interaction with CTLA-4 can inhibit T cell activation, helping to regulate immune responses.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Suvas, Susmit, et al. "Distinct role of CD80 and CD86 in the regulation of the activation of B cell and B cell lymphoma." Journal of Biological Chemistry 277.10 (2002): 7766-7775.