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Mouse Anti-Canine RAS Oncogene Family Member D2 (RASD2) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for canine RAS oncogene family member D2. It can be applied to WB; IHC and FACS assays of canine RAS oncogene family member D2.
Specifications
Target Information
Canine RAS oncogene family member D2, also known as KRAS, is a critical protein involved in cellular signaling pathways that regulate cell growth, differentiation, and survival. Mutations in RAS genes, including KRAS, are key oncogenic drivers in many cancers. KRAS, specifically, plays a distinct role in a tissue-type dependent manner, and oncogenic mutations in KRAS, such as Q61, are observed in various malignancies, including lung adenocarcinoma. These mutations lead to the hyperactivation of downstream signaling pathways like the RAF-MEK-ERK (MAPK) and PI3K-AKT cascades, promoting uncontrolled cell proliferation and survival, which are hallmarks of cancer.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.