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Mouse Anti-Swine CD16 Monoclonal Antibody

Cat. No.VD10H12

Product TypeAnimal-targeted Antibodies

Size

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Product Overview

O10H12 monoclonal antibody is specific for Swine CD16, also know as Swine FCGR3A or FCGRIII. It was purified by affinity chromatography on Protein A from tissue culture supernatant. It can be applied for Flow Cytometry (FC); Immunofluorescence (IF) and Immunoprecipitation (IP) .

Specifications

Application FC; IF; IP

Clonality Monoclonal Antibody

Classification Primary Antibody

Clone O10H12

Host Mouse

Target Species Swine

Species Reactivity Swine

Specificity Swine CD16

Isotype IgG1

Immunogen Swine peripheral blood leucocytes

Purification Protein A Purified

Purity ≥ 90% (SDS-PAGE)

Concentration 1.0 mg/mL

Conjugation Unconjugated

Preservative and Stabilizer 0.09% Sodium azide (NaN₃)

Buffer Phosphate buffered saline

Physical State Liquid

Target Information

Cluster of differentiation 16 (CD16), also known as FCGR3A is a receptor for the invariable Fc fragment of immunoglobulin gamma (IgG). CD16 is involved in the removal of antigen-antibody complexes from the circulation, as well as other responses, including antibody dependent cellular mediated cytotoxicity and antibody dependent enhancement of virus infections. CD16 could specifically bind to the porcine reproductive and respiratory syndrome disease virus-antibody immune complex and subsequently mediate internalization of the virus, resulting in the generation of progeny virus.

Target Swine CD16

Target Synonym FCGR3A; CD16A; FCG3; FCGR3; FCGRIII; FCR-10; FCRIII; FCRIIIA; IGFR3; IMD20; Fc fragment of IgG receptor IIIa; Fc gamma receptor IIIa; FcGRIIIA; CD16-II

Gene ID 406193

UniProt ID Q28942

Shipping and Storage

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt (up to 12 months).

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

References

Lithgow, Pamela, et al. "Correlation of cell surface marker expression with African swine fever virus infection." Veterinary microbiology 168.2-4 (2014): 413-419.