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Mouse Anti-Canine Protein Phosphatase 5 Catalytic Subunit (PPP5C) Monoclonal Antibody

Cat. No.VD11N18

Product TypeAnimal-targeted Antibodies

Size 100 μL

Product Overview

BioVenic mouse monoclonal antibody is specific for canine protein phosphatase 5 catalytic subunit. It can be applied to WB, ICC/IF, IHC and FACS assays of canine protein phosphatase 5 catalytic subunit.

Specifications

Application WB; ICC/IF; IHC; FACS
Clonality Monoclonal
Classification Primary Antibody
Clone S9N18
Host Mouse
Target Species Canine
Species Reactivity Canine
Specificity Canine Protein Phosphatase 5 Catalytic Subunit
Isotype IgG1
Immunogen Recombinant protein of protein phosphatase 5 catalytic subunit
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.09% Sodium Azide
Buffer Phosphate Buffered Saline, 1% BSA, 50% Glycerol
Physical State Liquid

Target Information

Canine protein phosphatase 5 catalytic subunit (PP5C) is a serine/threonine protein phosphatase that plays a role in cellular stress responses, glucocorticoid signaling, and DNA damage repair. It is unique among the PPP family as it contains a regulatory N-terminal tetratricopeptide repeat (TPR) domain that suppresses its activity through an autoinhibited conformation. PP5's function is modulated by interactions with molecular chaperones, such as Hsp90, which release autoinhibition and stimulate its phosphatase activity. This enzyme is involved in the dephosphorylation of proteins, including the regulation of kinases and steroid hormone receptors, making it a potential target for therapeutic interventions in diseases such as cancer.

Target Canine Protein Phosphatase 5 Catalytic Subunit
Target Synonym PPP5C; Serine/threonine-protein phosphatase
Gene ID 612199
UniProt ID A0A3Q7TWL3

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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