Mouse Anti-Porcine APBB1 Monoclonal Antibody

Porcine amyloid-beta precursor protein-binding family B member 1 (pAPBB1), also known as Fe65, is a multidomain adaptor protein that plays a significant role in the signaling pathways associated with the amyloid-beta precursor protein (AβPP) in pigs. pAPBB1 is involved in the regulation of neuronal function and survival, and it has been implicated in the processing of AβPP, which is crucial for maintaining cognitive health. This protein interacts with the intracellular domain of AβPP and is involved in the trafficking and metabolism of this protein, influencing the production of amyloid-beta peptides that are associated with neurodegenerative diseases such as Alzheimer's. pAPBB1 also plays a role in gene transcription regulation and cell signaling, contributing to processes like learning and memory.