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Rabbit Anti-Canine Cathepsin A (CTSA) Polyclonal Antibody

Cat. No.VD11N917

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for canine cathepsin A. It is antigen affinity purified. It can be applied to WB, IHC and IF/ICC assays of canine cathepsin A.

Specifications

Application WB; IHC; IF/ICC
Clonality Polyclonal
Classification Primary Antibody
Clone J20N5
Host Rabbit
Target Species Canine
Species Reactivity Canine
Specificity Canine Cathepsin A
Isotype IgG
Immunogen Recombinant protein of cathepsin A
Purification Antigen Affinity Purified
Conjugation FITC
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, 50% Glycerol
Physical State Liquid

Target Information

Canine cathepsin A (CTSA) is a lysosomal enzyme that plays a critical role in cellular metabolism and protein regulation. It functions primarily as a serine carboxypeptidase, cleaving peptide bonds at the carboxy-terminal end of proteins, which is essential for protein turnover and degradation. CTSA operates within the acidic environment of lysosomes, contributing to the breakdown of dysfunctional and surplus proteins, thereby preventing the accumulation of toxic aggregates.

Target Canine Cathepsin A
Target Synonym CTSA
Gene ID 611146
UniProt ID A0A8I3NUV8

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Kim, Jin-Wook, et al. "Leptin modulates the metastasis of canine inflammatory mammary adenocarcinoma cells through downregulation of lysosomal protective protein cathepsin A (CTSA)." International journal of molecular sciences 21.23 (2020): 8963.
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