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Mouse Anti-Porcine Mitochondrial Creatine Kinase (uMtCK) Monoclonal Antibody

Cat. No.VD8N176

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for porcine mitochondrial creatine kinase. It can be applied to WB assay of porcine mitochondrial creatine kinase.

Specifications

Application WB
Clonality Monoclonal
Classification Primary Antibody
Clone G4N39
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Porcine Mitochondrial Creatine Kinase
Isotype IgG
Immunogen Purified recombinant porcine mitochondrial creatine kinase protein fragments
Concentration 1 mg/mL
Conjugation Unconjugated
Physical State Liquid

Target Information

Mitochondrial creatine kinase (uMtCK), also known as ubiquitous mitochondrial creatine kinase, is an enzyme that plays a pivotal role in energy metabolism within the mitochondria of cells. This isoform of creatine kinase is found across various tissues, including heart and skeletal muscle, where it helps maintain energy homeostasis by catalyzing the transfer of a high-energy phosphate group from phosphocreatine to ADP, thereby generating ATP. uMtCK is particularly crucial during periods of high energy demand, such as muscle contraction or intense physical activity. Its function ensures that ATP is efficiently produced to meet the cell's immediate energy needs, supporting the cell's ability to perform work.

Target Porcine Mitochondrial Creatine Kinase
Target Synonym CKMT1A
Gene ID 100519994
UniProt ID F1SI77

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt. Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Meyer, Laudiene Evangelista, et al. "Mitochondrial creatine kinase activity prevents reactive oxygen species generation: antioxidant role of mitochondrial kinase-dependent ADP re-cycling activity." Journal of Biological Chemistry 281.49 (2006): 37361-37371.
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