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Mouse Anti-Canine Sonic Hedgehog (Shh) Monoclonal Antibody

Cat. No.VD11N154

Product TypeAnimal-targeted Antibodies

Size 100 μL

Product Overview

BioVenic mouse monoclonal antibody is specific for canine sonic hedgehog. It can be applied to WB and ICC/IF assays of canine sonic hedgehog.

Specifications

Application WB; ICC/IF
Clonality Monoclonal
Classification Primary Antibody
Clone S14N17
Host Mouse
Target Species Canine
Species Reactivity Canine
Specificity Canine Sonic Hedgehog
Isotype IgG1
Immunogen Recombinant protein of sonic hedgehog
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, 1% BSA, 50% Glycerol
Physical State Liquid

Target Information

Canine sonic hedgehog (SHH) is a signaling protein critical for embryonic development, tissue regeneration, and stem cell differentiation in dogs. It plays a significant role in the development of various tissues, including the nervous system, limbs, and mammary glands. SHH is also implicated in the progression of many tumor types, including canine mammary gland tumors, where its expression levels are significantly higher in malignant tissues compared to benign ones.

Target Canine Sonic Hedgehog
Target Synonym SHH
Gene ID 608860
UniProt ID A0A8I3NRD7

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Baldanza, Vincent E., et al. "Evaluation of canonical Hedgehog signaling pathway inhibition in canine osteosarcoma." PLoS One 15.4 (2020): e0231762.
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