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Mouse Anti-Porcine Prostaglandin E Receptor 4 (PTGER4) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for prostaglandin E receptor 4. It is affinity purified by protein A. It can be applied to WB, IF-P, IHC, FC and ELISA assays of prostaglandin E receptor 4.
Specifications
Target Information
Porcine prostaglandin E receptor 4 (pPTGER4), also known as the E-type prostanoid 4 receptor, is a pivotal G-protein coupled receptor (GPCR) that binds to prostaglandin E2 (PGE2). This receptor is integral in the modulation of inflammatory responses, pain sensation, and immune function within porcine physiology. The pPTGER4 is expressed in a variety of porcine tissues, including the brain, immune cells, and the urogenital system, suggesting its broad impact on the pig's biological processes. Activation of this receptor can lead to the inhibition of adenylyl cyclase, thereby reducing intracellular cAMP levels and subsequently influencing cellular signaling pathways.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Take, Yukinori, et al. "Prostaglandin E receptor 4 antagonist in cancer immunotherapy: mechanisms of action." Frontiers in immunology 11 (2020): 324.