Mouse Anti-Porcine PPARG Coactivator 1 Beta (PPARGC1B) Monoclonal Antibody

Porcine PPARG coactivator 1 beta (pPGC-1β), also known as peroxisome proliferator-activated receptor gamma coactivator 1-beta, is a transcriptional coactivator that plays a significant role in the regulation of energy metabolism, particularly in the context of fatty acid oxidation and glucose homeostasis. This protein is highly expressed in metabolically active tissues such as the liver, skeletal muscle, and adipose tissue, where it enhances the activity of nuclear receptors, including PPARs and ERRs. pPGC-1β functions by interacting with and stabilizing various transcription factors, thereby modulating the expression of genes involved in mitochondrial biogenesis, fatty acid metabolism, and oxidative phosphorylation. Its activation can lead to increased mitochondrial content and improved cellular respiration, making it a key player in the adaptive response to metabolic challenges.