Mouse Anti-Chicken Proteasome 26S Subunit Non-ATPase Regulatory Subunit 13 (PSMD13) Monoclonal Antibody

Chicken proteasome 26S subunit non-ATPase regulatory subunit 13 (PSMD13) is an integral component of the 26S proteasome, a cellular complex that degrades unneeded or damaged proteins. PSMD13 plays a crucial role in the structural maintenance and function of the proteasome, particularly in the regulation of protein homeostasis. Recent studies have highlighted the role of PSMD13 in immune response and inflammation. It has been shown to inhibit the NF-κB pathway by targeting TAK1, a key signaling molecule in the pathway, for K63-linked ubiquitination in fish models. This suggests that PSMD13 could be a regulator of innate immunity and inflammation, potentially influencing the body's response to pathogens.