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Mouse Anti-Chicken Histone H3 Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for histone H3. It is affinity purified by protein A. It can be applied to WB, IHC and ELISA assays of histone H3.
Specifications
Target Information
Chicken histone H3 (cH3) is a variant of the histone protein H3 found in chickens, which plays a central role in the packaging and organization of DNA within the nucleus of cells. Histones are highly conserved proteins that, together with DNA, form the nucleosome, the basic unit of chromatin structure. cH3, like its mammalian counterparts, is involved in the regulation of gene expression, DNA replication, and DNA repair. It contains a positively charged amino-terminal tail that interacts with the negatively charged DNA, facilitating the wrapping of DNA around the histone octamer. This interaction is essential for the compaction of DNA within the cell nucleus and for the regulation of gene activity.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Myers, Fiona A., et al. "Targeted and extended acetylation of histones H4 and H3 at active and inactive genes in chicken embryo erythrocytes." Journal of Biological Chemistry 276.23 (2001): 20197-20205.