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Mouse Anti-Porcine Cofilin 1 Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for cofilin 1. It is affinity purified by protein A. It can be applied to WB, IF, IHC and ELISA assays of cofilin 1.
Specifications
Target Information
Porcine cofilin 1 is an actin-binding protein that plays a pivotal role in the dynamic remodeling of the cytoskeleton in pig cells. It is particularly influential in the regulation of actin filament turnover, which is essential for various cellular processes such as cell motility, endocytosis, and cytokinesis. pCofilin1 promotes the disassembly of actin filaments by severing and depolymerizing them, thus increasing the availability of monomeric actin for new filament assembly. Its activity is tightly regulated by various mechanisms, including phosphorylation, which inhibits its actin-depolymerizing function.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Shishkin, Sergey, et al. "Cofilin-1 and other ADF/cofilin superfamily members in human malignant cells." International journal of molecular sciences 18.1 (2016): 10.