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Mouse Anti-Porcine Dystroglycan 1 (DAG1) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for dystroglycan 1. It is affinity purified by protein A. It can be applied to WB, IF, IHC and ELISA assays of dystroglycan 1.
Specifications
Target Information
Porcine dystroglycan 1 (pDAG1) is a key component of the dystrophin-glycoprotein complex, which is essential for maintaining the integrity of muscle fibers and the stability of the sarcolemma. pDAG1, as a transmembrane protein, serves as a crucial link between the extracellular matrix and the actin cytoskeleton, playing a vital role in muscle cell adhesion, signaling, and overall muscle function. This protein is particularly important in pigs, where it contributes to the structural stability of skeletal and cardiac muscles. pDAG1 is also implicated in the proper formation and maintenance of the neuromuscular junction, which is critical for the transmission of nerve signals to muscle cells.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Durbeej, Madeleine, et al. "Biochemical characterization of the epithelial dystroglycan complex." Journal of Biological Chemistry 274.37 (1999): 26609-26616.