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Rabbit Anti-Bovine Interferon Tau (IFNt) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for bovine interferon tau. It is affinity purified by protein A. It can be applied to WB, IHC and IF/ICC assays of bovine interferon tau.
Specifications
Target Information
Bovine interferon tau (IFNT) is a type I interferon crucial for maternal recognition of pregnancy in ruminants. It is secreted by the mononuclear trophectoderm cells of the developing embryo during the peri-implantation period. IFNT acts as a key signal to extend corpus luteum function, maintaining progesterone production essential for pregnancy. It binds to type-1 interferon receptors (IFNAR1 and IFNAR2), activating the JAK-STAT signaling pathway and inducing interferon-stimulated genes (ISGs) with antiviral and immunosuppressive roles. This unique cytokine also influences endometrial gene expression, preparing the uterus for implantation.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Talukder, Anup K., et al. "Oviduct epithelium induces interferon-tau in bovine Day-4 embryos, which generates an anti-inflammatory response in immune cells." Scientific Reports 8.1 (2018): 7850.