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Rabbit Anti-Porcine IgG (H+L) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for porcine IgG (H+L). It can be applied to ICC, IHC and WB assays of porcine IgG (H+L).
Specifications
Target Information
Porcine IgG (H+L) refers to the immunoglobulin G found in pigs, which is composed of two heavy chains and two light chains. Pigs have multiple IgG subclasses, including IgG1, IgG2a, IgG2b, IgG2c, IgG3, IgG4, IgG5a, IgG5b, and IgG5c, with recent genomic analyses indicating at least nine subclasses. These subclasses vary in their effector functions, such as complement activation, antibody-dependent cellular cytotoxicity (ADCC), and antibody-dependent cellular phagocytosis (ADCP), which are critical for the immune response.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid exposure to light. Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Spoerry, Christian, et al. "Identification and characterization of IgdE, a novel IgG-degrading protease of Streptococcus suis with unique specificity for porcine IgG." Journal of Biological Chemistry 291.15 (2016): 7915-7925.