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Mouse Anti-Canine CDGSH Iron-Sulfur Domain 1 (CISD1) Monoclonal Antibody

Cat. No.VD11N134

Product TypeAnimal-targeted Antibodies

Size 100 μL

Product Overview

BioVenic mouse monoclonal antibody is specific for canine CDGSH iron-sulfur domain 1. It can be applied to WB, ICC/IF and FACS assays of canine CDGSH iron-sulfur domain 1.

Specifications

Application WB; ICC/IF; FACS
Clonality Monoclonal
Classification Primary Antibody
Clone S13N86
Host Mouse
Target Species Canine
Species Reactivity Canine
Specificity Canine CDGSH Iron-Sulfur Domain 1
Isotype IgG1
Immunogen Recombinant protein of CDGSH iron-sulfur domain 1
Concentration 0.72 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, 1% BSA, 50% Glycerol
Physical State Liquid

Target Information

Canine CDGSH iron-sulfur domain 1 (CISD1) is a protein that contains a CDGSH iron-sulfur domain and is known to bind a redox-active [2Fe-2S] cluster. This protein is localized to the outer membrane of mitochondria and is thought to play a role in the regulation of oxidation. CISD1 has been implicated in a variety of diseases, including diabetes, obesity, cancer, cardiovascular disease, and neurodegeneration in humans. It is involved in the regulation of mitochondrial iron and reactive oxygen species (ROS) metabolism, a function that is proposed to be conserved among plant and animal NEET proteins. In dogs, CISD1 may serve a similar role, influencing cellular redox balance and potentially playing a part in diseases associated with mitochondrial dysfunction and oxidative stress.

Target Canine CDGSH Iron-Sulfur Domain 1
Target Synonym CISD1; Iron-binding zinc finger CDGSH type domain-containing protein
Gene ID 119871454
UniProt ID A0A8C0PWB7

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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