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Mouse Anti-Porcine CD4 Monoclonal Antibody-[APC]

Product Overview

BioVenic mouse monoclonal antibody is specific for porcine CD4. It can be applied to FCM, IHC and IP assays of porcine CD4.

Specifications

Application FCM; IHC; IP

Clonality Monoclonal

Classification Primary Antibody

Clone L12N20

Host Mouse

Target Species Porcine

Species Reactivity Porcine

Specificity Porcine CD4

Isotype IgG2

Immunogen Swine thymocytes

Purity > 90%

Concentration 0.1 mg/mL

Conjugation APC

Preservative and Stabilizer < 0.1% Sodium Azide

Buffer Phosphate Buffered Saline with Stabilizer

Physical State Liquid

Target Information

Porcine CD4 is a cell surface glycoprotein that serves as a co-receptor on the surface of T-helper cells within the porcine immune system. It is crucial for the proper functioning of these cells, which play a central role in the adaptive immune response. pCD4 aids in the interaction between the T cell receptor (TCR) and the major histocompatibility complex class II (MHC II) molecules on antigen-presenting cells (APCs). This interaction is essential for the activation of T-helper cells, leading to the initiation of downstream signaling pathways that result in T cell proliferation, differentiation, and production of cytokines.

Target Porcine CD4

Gene ID 404704

Shipping and Storage

This product is shipped with ice gel packs. Store at 2°C - 8°C (up to 12 months) on receipt. Avoid exposure to light and do not freeze.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Chung, Chungwon J., et al. "Pigs that recover from porcine reproduction and respiratory syndrome virus infection develop cytotoxic CD4+ CD8+ and CD4+ CD8-T-cells that kill virus infected cells." Plos one 13.9 (2018): e0203482.