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Mouse Anti-Porcine Succinate Dehydrogenase Complex Subunit A (SDHA) Monoclonal Antibody

Cat. No.VD8N270

Product TypeAnimal-targeted Antibodies

Size

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Product Overview

BioVenic mouse monoclonal antibody is specific for succinate dehydrogenase complex subunit A. It is affinity purified by protein A. It can be applied to WB, IHC, IF and ELISA assays of succinate dehydrogenase complex subunit A.

Specifications

Application WB; IF; IHC; ELISA

Clonality Monoclonal

Classification Primary Antibody

Clone G6N14

Host Mouse

Target Species Porcine

Species Reactivity Porcine

Specificity Succinate Dehydrogenase Complex Subunit A

Isotype IgG1

Immunogen Recombinant protein of succinate dehydrogenase complex subunit A

Purification Protein A Purified

Concentration 2100 μg/mL

Conjugation Unconjugated

Preservative and Stabilizer 0.02% Sodium Azide

Buffer Phosphate Buffered Saline with 50% Glycerol, pH 7.3

Physical State Liquid

Target Information

Porcine succinate dehydrogenase complex subunit A (SDHA) is a key component of the succinate dehydrogenase enzyme, also known as Complex II, which plays a central role in the pig's mitochondrial respiratory chain. This enzyme is involved in the tricarboxylic acid (TCA) cycle, also known as the citric acid cycle or Krebs cycle, and is essential for cellular respiration and energy production. SDHA functions by catalyzing the oxidation of succinate to fumarate, and in the process, it transfers electrons to coenzyme Q (CoQ), which are then used in the electron transport chain to generate ATP, the cell's primary energy currency. This subunit is crucial for maintaining the structural integrity and functionality of the entire enzyme complex.

Target Succinate Dehydrogenase Complex Subunit A

Target Synonym FP; SDH2

Gene ID 780433

UniProt ID Q0QF01

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Wang, Lin, et al. "Upregulation of Succinate Dehydrogenase (SDHA) Contributes to Enhanced Bioenergetics of Ovarian Cancer Cells and Higher Sensitivity to Anti-Metabolic Agent Shikonin." Cancers 14.20 (2022): 5097.