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Rabbit Anti-Bovine Transportin 1 (TNPO1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for bovine transportin 1. It is affinity purified by protein A. It can be applied to WB, IHC and IF/ICC assays of bovine transportin 1.
Specifications
Target Information
Bovine transportin 1 (TNPO1), also known as karyopherin β2, is a nuclear import receptor that plays a significant role in nucleo-cytoplasmic transport. It interacts with nuclear localization signals (NLS) to target nuclear proteins to the nucleus. TNPO1 recognizes the PY (proline-tyrosine) NLS motif in cargo proteins, facilitating their transport into the nucleus. This receptor is crucial for the nuclear import of various proteins, including RNA-binding proteins like hnRNP A1 and FUS, and is involved in processes such as DNA repair, cell division, and immune regulation.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.