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Rabbit Anti-Bovine Angiopoietin 2 (ANGPT2) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for bovine angiopoietin 2. It is affinity purified by protein A. It can be applied to WB, IHC and IF/ICC assays of bovine angiopoietin 2.
Specifications
Target Information
Bovine angiopoietin 2 (ANGPT2) is a key player in vascular development and function in cattle. It is involved in the extravasation of neutrophils, which is significant for controlling the amount of somatic cells in milk. ANGPT2 acts as a partial agonist/antagonist of Tie2 signaling in the endothelium, which can influence vascular stability and angiogenesis. Elevated levels of ANGPT2 are associated with conditions like sepsis and cancer, where it contributes to disease progression by blocking Ang1-mediated signaling, leading to vascular dysfunction.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Oh, Hideyasu, et al. "Hypoxia and vascular endothelial growth factor selectively up-regulate angiopoietin-2 in bovine microvascular endothelial cells." Journal of Biological Chemistry 274.22 (1999): 15732-15739.